Monday, March 25, 2019

MedStar Diabetes Research Funds Supports Research for Stromal Cells in Diabetes


Congratulations are in order to the research team from MedStar Union Memorial Hospital and the Orthobiologic Labatory! The team, led by Zijun Zhang, included Lew Schon, Young Cho, Reed Mitchell, Sharada Paudel, and Tyler Feltham, recently published their research, "Compromised Antibacterial Function of Multipotent Stromal Cells in Diabetes ", in Stem Cells and Development.

This research was funded by the MedStar Diabetes Research Grant in 2016. The study analyzes multipotent stormal cells (MSCs) of persons with diabetes and examines the weakened ability to fight off bacterial infection.  The study team isolated MSCs from the bone marrow of 9 diabetic and non-diabetic donors.  These cells were examined for bacterial growth and treated with or without cultures of E. coli.  The results concluded that MSCs of persons with diabetes are deficient in antibacterial infection, including the diminished potential to fight off the growth of bacteria.

You can read more about this great work in the press release here.

**The Request For Proposal (RFP) is now available for the 2019 MedStar Diabetes Research Grant.  Applications are due by 11:59 PM on May 13, 2019. For more information on Intramural Grant Opportunities, please visit our website.**

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